The relationship or encounter between the whites and the Indians in Virginia went well at first. This established many of the patterns that
characterized later Indian-white relations in North America, including disease,
warfare, and removal. Indian societies undertook their own major changes due to disease, trade, and warfare. For a time after the
Atlantic coastal tribes were nearly wiped out, the larger Indian peoples of the
Appalachian area created a forbidding barrier to white expansion.
